The combined use of electrocardiography, echocardiography and cardiac magnetic resonance imaging in left atrium evaluation among beta-thalassemia patients

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Beta-thalassemia major (β-TM) patients are subjected to iron overload as a consequence chronic blood transfusions. The redundant affects, among other organs, the heart resulting in myocardial dysfunction. Iron deposition does not only affect ventricular myocardium but atrial well. According current practice, overall status is estimated by calculating T2* at middle section septum using cardiac magnetic resonance imaging (CMR). Current CMR technology limits direct estimation status. Purpose study evaluates left function novel echocardiographic techniques and correlates these findings with data. Methods 37 β-TM (mean age 41.17 years (SD = 8.33), 51.4% male), were electrocardiography, echocardiography P wave axis, PR segment duration, volume index (LAVI), strain reservoir phase (LASr) measured. Results No correlation between LASr (r 0.253, p 0.131) or LAVI 0.044, 0.796) found. However, was found parameters -0.676, <0.001). axis did correlate any parameter, while duration correlated -0.399, 0.015). Regression analysis revealed (r2 0.457, Conclusions suggests that despite undisputed contribution load estimation, it may be less accurate estimation. Considering limitations regarding thin right walls, our highlights role speckle tracking combination for more comprehensive evaluation patients. Correlation table 0,151 (p 0,373) 0,112 0.,508) -0,140 0,410) -0,117 0,489) 0,051 0,766) 0,278 0,096) -0,399 0,015) 0,044 0,796) 0,253 0,131) -0,676 <0,001) T2*: obtained (ml/m2) Figure.